Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Effectiveness and Safety of Tirzepatide Among Participants With Obesity With or Without Type 2 Diabetes Mellitus (T2DM)

This is a prospective, multicenter, real-world study conducted in Bangladesh to assess the effectiveness and safety of Tirzepatide compared to structured lifestyle interventions, including dietary modifications and exercise, in obese adults with or without Type 2 Diabetes Mellitus (T2DM). The study aims to determine whether treatment with Tirzepatide results in superior weight reduction outcomes compared to lifestyle-based approaches. Adult participants (≥18 years) with a body mass index (BMI) ≥25 kg/m² and no prior exposure to GLP-1 receptor agonists will be enrolled at the discretion of the treating physician. Eligible participants will receive either once-weekly Tirzepatide or participate in lifestyle intervention programs aligned with standard clinical care.

Participants needed: 364
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Dr. Md. Alimur RezaUpdated: Aug 3, 2025Locations: 3
Eligibility criteria

Adult patients of both sexes, aged ≥18 years. [+3]

Diagnosis of diabetes other than Type 2 Diabetes Mellitus. [+8]

Status: Recruiting

Efficacy and Safety of Atorvastatin and Ezetimibe (10/10mg) Fixed Dose Combination Versus Atorvastatin (20mg) Monotherapy in Bangladeshi Population

The goal of this clinical trial is to evaluate the efficacy and safety of a fixed-dose combination of atorvastatin (10 mg) and ezetimibe (10 mg) compared to atorvastatin (20 mg) monotherapy in the Bangladeshi population. Researchers will compare atorvastatin (10 mg) and ezetimibe (10 mg) to atorvastatin (20 mg) monotherapy to see if atorvastatin (10 mg) and ezetimibe (10 mg) FDC works to treat dyslipidemia. Participants will: * Take a fixed-dose combination of atorvastatin (10 mg) and ezetimibe (10 mg) compared to atorvastatin (20 mg) monotherapy for 3 months * Follow-up visits at 6 weeks and 12 weeks for checkups and tests

Participants needed: 500
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Dr. Md. Alimur RezaUpdated: Jul 29, 2025Locations: 1
Eligibility criteria

Men and women aged >18 years. [+4]

History of hypersensitivity to any study drugs. [+4]