Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

GB268 Monotherapy or Combination Therapy for Locally Advanced/Metastatic Breast Cancer (Phase Ib/Ⅱ)

This is a Phase Ib/II, open-label, multi-cohort, multi-center study to evaluate the safety, tolerability, and preliminary anti-tumor activity of GB268, a biological product, as monotherapy or in combination with other therapies in patients with locally advanced unresectable or metastatic breast cancer.

Participants needed: 270
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Eddingpharm (Zhuhai) Co., Ltd.Updated: Jul 31, 2026
Eligibility criteria

Age ≥ 18 years, male or female. [+9]

Prior anti-cancer therapy within specified washout periods. [+24]

Status: Recruiting

A Dose-exploration Study of EDP167 in HoFH

EDP167 is a double-stranded small interfering RNA (siRNA) drug targeting angiopoietin-like 3 protein (ANGPTL3), which may bring benefits for patients with dyslipidemia conditions. This is a dose exploration study in Homozygous Familial Hypercholesterolaemia (HoFH) patients to evaluate the efficacy and safety and pharmacokinetics (PK)/pharmacodynamics (PD) profiles of multiple EDP167 injections.

Participants needed: 20
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Eddingpharm (Zhuhai) Co., Ltd.Updated: May 20, 2026Locations: 1
Eligibility criteria

Age ≥18 years old, male or female, and weight ≥40 kg. [+7]

Allergic to the drug in this study, its components or similar drugs. [+18]