Status: Recruiting
Low-Dose Radiotherapy for Alzheimer's Disease
To evaluate the safety and tolerability of low-dose whole brain radiotherapy (WBRT) delivered as an induction course of 0.3 Gy × 10 fractions (3.0 Gy total) followed by 12 months of monthly maintenance LDRT (0.3 Gy × 10 fractions; 3.0 Gy total) in patients with Alzheimer's disease or dementia with inflammatory components
Participants needed: 50
Trial details
Phase: Phase 1, Phase 2Age: 50+Biological sex: AllType: InterventionalSponsor: Evan ThomasUpdated: Jul 9, 2026Locations: 1
Eligibility criteria
Age ≥50 years at time of enrollment [+8]
Prior whole brain or partial brain radiotherapy of any dose at any time [+11]