Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Contact Lens-Wearing Dry Eye Subjects Who Are Treated With Acoltremon 0.003%

Dry Eye Disease is a multifaceted condition which has symptoms such as eye dryness, burning, and stinging sensation in the eyes. As well as clinical diagnosis such as a decreased ability to create tear film. Despite improvements in Contact Lenses (CL) DED still is responsible for a large percentage of CL dropouts due to discomfort. Thus, the purpose of this study is to determine if acoltremon 0.003% can improve the frequency and severity of DED symptoms in CL wearers.

Participants needed: 50
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Eye Research Associates, LLCUpdated: Oct 8, 2026
Eligibility criteria

• Adult subjects who are ≥18 years of age. [+9]

Any history of acoltremon 0.003% use. [+13]

Status: Recruiting

Evaluation of Lacrifill

Dry Eye Disease is defined as "a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface. It is accompanied by increased osmolarity of the tear film and inflammation of the ocular surface.' 'By the The Tear Film and Ocular Surface Society. Despite there being a number of factors that impact DED however one factor that has been considered likely is that of a complication from ocular surgery itself. Which can cause both corneal nerve, and ocular surface damage. Therefore this study aims to determine how Lacrfill performs in preventing post-operative dry eye symptoms in those who have recently had unilateral cataract surgery.

Participants needed: 40
Trial details
Phase: Phase 4Age: 18-80Biological sex: AllType: InterventionalSponsor: Eye Research Associates, LLCUpdated: Sep 25, 2026Locations: 2
Eligibility criteria

Adults ≥18 years of age. [+5]

Known systemic health conditions that are known to alter tear film physiology (e... [+7]