Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
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Status: Not yet recruiting

Dyadic Cognitive Intervention for Older Adults With Cognitive Impairment and Their Spouses

The goal of this randomized controlled clinical trial is to learn if a couple-centered cognitive intervention program can improve cognitive health, reduce caregiving burden, and support overall well-being for community-dwelling older adults (aged 60 and above) with mild cognitive impairment and their spouses. The main questions it aims to answer are: * Does the couple-based cognitive intervention improve the cognitive function of older adults with mild cognitive impairment? * Can the intervention reduce the caregiving burden experienced by spouses who care for a partner with cognitive impairment? * Can the intervention help reduce depressive symptoms, improve quality of life, and strengthen the ability of couples to cope with the disease together? Researchers will compare two groups of participants: the intervention group receives the couple-based cognitive program in addition to regular community health education, while the control group receives only regular community health education. The study will test whether the intervention leads to better health and well-being outcomes for both the older adults with cognitive impairment and their spouse caregivers. Participants will: * Be randomly assigned to either the intervention group or the control group * If in the intervention group: join an 8-week structured couple intervention with their spouse. The program covers cognitive health knowledge, joint memory and thinking exercises, communication and coping skill practice, and guidance for shared healthy daily habits * If in the control group: receive standard community health education about cognitive impairment prevention and care * Complete health and well-being assessments at the start of the study, 3 months after the intervention, and 6 months after the intervention. Assessments include tests of cognitive function, daily living ability, mood, quality of life, how well couples cope with the disease together, and how much burden spouses feel from providing day-to-day care.

Participants needed: 136
Trial details
Age: 60+Biological sex: AllType: InterventionalSponsor: Gansu University of Chinese MedicineUpdated: Oct 13, 2026Locations: 1
Eligibility criteria

Permanent residents of the Tuanjie Xincun community (with a residence duration o... [+4]

Either member of the couple has a severe systemic disease that renders them unab...

Status: Not yet recruiting

Sedentary Behavior Intervention for Older Adults With Coronary Heart Disease and Frailty

This study aims to evaluate the feasibility and effectiveness of a sedentary behavior intervention based on the Integrated Theory of Health Behavior Change (ITHBC) in older adults with coronary heart disease and frailty. Participants will be randomly assigned to an intervention group or a control group. The intervention is designed around the three core components of ITHBC-knowledge and beliefs, self-regulation skills and abilities, and social facilitation-to help participants reduce sedentary behavior, improve physical activity, and enhance their ability to manage health-related behaviors. The study will include a 1-month intervention period followed by a 2-month follow-up period, with a total study duration of 3 months for each participant. Changes in sedentary behavior and other health-related outcomes will be assessed throughout the study period.

Participants needed: 64
Trial details
Age: 60+Biological sex: AllType: InterventionalSponsor: Gansu University of Chinese MedicineUpdated: Aug 13, 2026Locations: 1
Eligibility criteria

Age 60 years or older. [+6]

Currently participating in another research study. [+5]