Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Phase II Study of RP2 as Immunoprevention in High-Risk Oral Precancerous Disease

The goal of this study is to understand the safety, tolerability, and potential efficacy of an injected immune therapy called RP2 to treat oral precancer conditions and prevent progression to an oral cancer. The name of the study drug involved in this study is: -RP2 (a genetically modified live Herpes Simplex V-1 strain)

Participants needed: 25
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Glenn J. HannaUpdated: Apr 23, 2026Locations: 2
Eligibility criteria

Proliferative leukoplakia (PL) [+15]

Prior treatment with an oncolytic virus therapy. [+10]

Status: Recruiting

A Phase 2 Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers

The goal of this study is to evaluate the efficacy and safety of Ivonescimab in participants with advanced, metastatic salivary gland cancers. The name of the study drug involved in this study is: -Ivonescimab (a type of antibody)

Participants needed: 35
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Glenn J. HannaUpdated: Jul 29, 2025Locations: 2
Eligibility criteria

Participants must have histologically confirmed salivary gland carcinoma (any hi... [+18]

Participant has known active central nervous system (CNS) metastases and/or carc... [+18]