Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Preoperative Pelvic Floor Muscle Training in Female Urinary Incontinence

Pelvic floor muscles (PFM) play a crucial role in supporting pelvic organs and maintaining continence. Weakness in these muscles can lead to dysfunctions such as pelvic organ prolapse, urinary incontinence (UI), and sexual or anorectal disorders. UI, defined as the involuntary loss of urine, is common globally and classified as stress, urge, or mixed incontinence. Stress urinary incontinence (SUI) - the most prevalent type among women - occurs during activities that increase intra-abdominal pressure. Risk factors include female sex, aging, obesity, smoking, chronic constipation, previous gynecological surgeries, and childbirth. Treatment options for SUI include conservative and surgical methods. Pelvic floor training (PFT), first described by Arnold Kegel in 1948, is a conservative approach that strengthens PFM and alleviates symptoms. Although surgery is often used for SUI, with over 200 procedures described, this study aims to evaluate the preoperative effectiveness of intensive PFT in women with SUI. It will assess changes in muscle function and symptoms before surgery, guiding pelvic rehabilitation strategies to potentially reduce surgical burden and improve outcomes.

Participants needed: 60
Trial details
Age: 18-65Biological sex: FemaleType: InterventionalSponsor: Gulhane School of MedicineUpdated: May 8, 2025Locations: 1
Eligibility criteria

Being a woman between the ages of 18-65 [+6]

Not volunteering to participate [+6]

Status: Recruiting

Can Lumbar Mulligan Mobilization Improve Gait, Balance, and Trunk Position Sense After Stroke?

Stroke is a pathology caused by disturbances in the brain's arterial circulation, leading to high morbidity rates. Individuals who experience a stroke often face neurological impairments such as motor, sensory, and cognitive dysfunctions, which negatively impact muscle strength, postural control, sensation, and gait, reducing their independence in daily activities. Balance deficits in stroke patients increase the risk of falls and contribute to a fear of falling. Improving balance control is a key goal in rehabilitation. The importance of the trunk in balance control and rehabilitation is well-established, as it plays a central role in maintaining stability. In individuals with restricted lumbar mobility, weakened trunk muscles and altered muscle activation can lead to a reduction in proprioception, hip strategy, and spinal stabilization, further impairing balance. Combining conventional exercise approaches with other rehabilitation techniques has been shown to yield more effective outcomes. This study aims to investigate the effects of Mulligan-based lumbar spine mobilization on balance, trunk position sense, and gait in individuals with stroke.

Participants needed: 40
Trial details
Age: 30-65Biological sex: AllType: InterventionalSponsor: Gulhane School of MedicineUpdated: Mar 20, 2025Locations: 1
Eligibility criteria

Diagnosed with stroke by a neurologist. [+5]

History of musculoskeletal disorders affecting the spine (e.g., cancer, scoliosi... [+3]

Status: Recruiting

Examining the Relationship Between Physical Activity Levels and Chronotype Tendencies in Individuals With Alcohol Dependence

Alcohol use disorders are characterized by excessive alcohol consumption and loss of control and are associated with high mortality and disease burden. The relationship between physical activity and alcoholism is complex, and low physical activity has been shown to be linked to alcohol consumption. Additionally, individuals' circadian rhythms (chronotypes) may influence alcohol consumption habits; Evening-type individuals are more likely to consume alcohol. This study aims to examine the relationship between physical activity levels and chronotype trends in individuals with alcohol addiction.

Participants needed: 207
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Gulhane School of MedicineUpdated: Feb 27, 2025Locations: 1
Eligibility criteria

Age: Being between 18-65 years old. [+2]

Active Psychiatric Diseases: For example, individuals with active psychiatric di... [+1]

Status: Not yet recruiting

Acupressure Mat on Perceived Stress, Sleep Quality and Premenstrual Symptoms

Purpose of the study: To examine the effect of acupressure mat on perceived stress, sleep quality and premenstrual symptoms in students with premenstrual syndrome. Hypotheses of the study; In the post-test and follow-up test between students who were applied acupressure mat and those who were applied plain mat; H10: There is no difference in terms of severity of premenstrual symptoms. H20: There is no difference in terms of perceived stress. H30: There is no difference in terms of sleep quality.

Participants needed: 42
Trial details
Biological sex: FemaleType: InterventionalSponsor: Gulhane School of MedicineUpdated: Oct 16, 2024
Eligibility criteria

Using medication and/or non-medical methods to cope with PMS [+2]

Participants wanting to withdraw from the study at any stage of the study [+3]