Clinical trials

8

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study Investigating Gingival Crevicular Fluid Biomarkers Following Use of a Commercially Available Toothpaste Containing Stannous Fluoride

The aim of this study is to evaluate the feasibility, sensitivity, and interpretability of gingival crevicular fluid (GCF) cytokine biomarkers as early indicators of tissue recovery following use of commercial dentifrice compared with a standard fluoride dentifrice in experimental gingivitis model, after 14 days twice daily use.

Participants needed: 20
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: HALEONUpdated: Oct 9, 2026Locations: 1
Eligibility criteria

Participant provision of a signed and dated informed consent document indicating... [+5]

A participant who is an employee of the investigational site, either directly in... [+18]

Status: Recruiting

A Study to Assess the Efficacy of an Experimental Mouthwash Used With a Marketed Whitening Toothpaste on Stain Build-up

The aim of this clinical study is to evaluate the efficacy of an experimental mouthwash used with a marketed whitening toothpaste or a marketed regular fluoride toothpaste, compared to a marketed regular fluoride toothpaste alone, in preventing extrinsic dental stain build-up.

Participants needed: 360
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: HALEONUpdated: Oct 7, 2026Locations: 1
Eligibility criteria

Participant provision of a signed and dated informed consent document indicating... [+7]

Participant who is an employee of the investigational site, either directly invo... [+24]

Status: Not yet recruiting

A Study to Visualize Multi-Symptom Allergy in Adults With Seasonal Allergic Rhinitis

This study is designed to visualize the response to use of fluticasone propionate nasal spray (Flonase Allergy Relief) to relieve facial allergy symptoms in individuals with moderate to severe seasonal allergic rhinitis (SAR).

Participants needed: 16
Trial details
Phase: Phase 4Age: 18-65Biological sex: AllType: InterventionalSponsor: HALEONUpdated: Sep 14, 2026Locations: 1
Eligibility criteria

Participant must give their signed and dated written informed consent to partici... [+8]

An employee of the investigational site, either directly involved in the conduct... [+28]

Status: Not yet recruiting

The Study to Evaluate the Plaque Control and Anti-Gingivitis Efficacy of a Toothpaste in Chinese Population

The aim of this study is to evaluate the efficacy of the test toothpaste compared to a regular fluoride toothpaste in the reducing gingivitis and plaque accumulation in Chinese participants with plaque-induced gingivitis.

Participants needed: 120
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: HALEONUpdated: Sep 11, 2026Locations: 1
Eligibility criteria

Provision of a signed and dated informed consent document indicating that the pa... [+3]

A participant who is an employee of the investigational site, either directly in... [+30]

Status: Not yet recruiting

A Clinical Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity

The primary purpose of this study is to demonstrate the clinical efficacy of Test Toothpaste in reducing dentin hypersensitivity (DH) to an evaporative (air) stimulus, compared to a sodium fluoride reference toothpaste, after 8 weeks twice daily use.

Participants needed: 192
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: HALEONUpdated: Sep 3, 2026Locations: 1
Eligibility criteria

Participant provision of signed and dated informed consent before any study proc... [+12]

Participant is an employee of the investigator site directly involved in the con... [+34]

Status: Recruiting

A Study to Evaluate Ibuprofen (IBU) 62.5 mg and Acetaminophen (APAP) 125 mg/5 ml in an Oral Liquid Suspension Fixed-Dose Combination Product in Children Aged 6 to 11 Years

The purpose of this study will be to characterize the pharmacokinetic (PK) profile of the Fixed-Dose Combination (FDC) IBU 62.5 milligram (mg)/APAP 125 mg per 5 milliliter (mL) suspension in children 6 to 11 years of age, inclusive, to satisfy Pediatric Research Equity Act (PREA) requirements.

Participants needed: 12
Trial details
Phase: Phase 1Age: 6-11Biological sex: AllType: InterventionalSponsor: HALEONUpdated: Jun 30, 2026Locations: 1
Eligibility criteria

Participant with at least one acute, painful condition (e.g., minor aches and pa... [+9]

Participants with evidence or history of clinically significant hematological, r... [+21]

Status: Recruiting

A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers

The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.

Participants needed: 375
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: HALEONUpdated: Apr 28, 2026Locations: 1
Eligibility criteria

Participant who has provided consent indicating they have been informed of all p... [+5]

Anyone who has any chronic health conditions that could impact their participati... [+8]

Status: Recruiting

A Clinical Study to Assess the Effectiveness of Use of Three Experimental Denture Adhesives Compared to Using No-Adhesive

The aim of the proposed clinical study is to investigate the efficacy of three experimental denture adhesive creams to improve denture hold over a period of 13 hours.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: HALEONUpdated: Apr 9, 2026Locations: 1
Eligibility criteria

Participant provision of a signed and dated informed consent document indicating... [+6]

A participant who is an employee of the investigational site, either directly in... [+10]