Clinical trials

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Condition / disease
Location
Status: Recruiting

To Assess the Efficacy and Safety of Utilizing Galactose-deficient IgA1 Biomarker Changes to Guide Pathogenic IgA-targeted Therapeutic Strategies

The goal of this open-label, randomized study is to evaluate the efficacy and safety of the personalized treatment model in which Gd-IgA1 is dynamically monitored to guide medication adjustment in progressive IgAN patients treated with Nefecon or telitacicept. Researchers will compare two groups of participants: those who have Gd-IgA1 checked regularly during treatment, and those who do not. This is to find out if regular Gd-IgA1 checks can help doctors adjust medication better and get better treatment results.

Participants needed: 374
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Hong ZhangUpdated: Sep 16, 2026Locations: 1
Eligibility criteria

Male or female, between 18 and 75 years age; [+5]

Secondary IgA nephropathy (excluding IgA vasculitis) caused by ankylosing spondy... [+19]