Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement

Brief Summary The goal of this clinical trial is to learn if nurse-led telehealth consultations can help detect complications and support recovery after total knee replacement surgery. The study will compare telehealth nursing consultations to traditional in-person nursing visits. The main questions it aims to answer are: * Can nurse-led telehealth detect post-surgery complications as well as or better than in-person consultations? * Does telehealth nursing support better or equivalent recovery outcomes and patient satisfaction compared to in-person care? Participants will: * Be adults who had their first total knee replacement surgery. * Receive follow-up care either through telehealth consultations using the HA Go mobile app or through traditional face-to-face nurse visits in the outpatient clinic. * Attend scheduled consultations and provide information about their recovery and any complications they experience. * Complete surveys about their satisfaction with the care they receive. This study will help determine if telehealth nursing consultations can provide safe, effective, and convenient follow-up care for patients after knee replacement surgery, potentially improving access and reducing travel burdens.

Participants needed: 98
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Hospital Authority, Hong KongUpdated: Jan 5, 2026Locations: 1
Eligibility criteria

Adults aged 18 years or older [+6]

Undergoing bilateral or revision total knee replacement surgery [+5]

Status: Recruiting

Faricimab Quarterly Maintenance for Neovascular Age Related Macular Degeneration

We aimed to investigate the success rate of a planned quarterly (every 12-16 weeks) faricimab injection schedule, following a disease inactivity achieved after initial 2-4 loading doses of faricimab, for nAMD to achieve stability without recurrence at a tertiary eye centre.

Participants needed: 40
Trial details
Phase: Phase 4Age: 50+Biological sex: AllType: InterventionalSponsor: Hospital Authority, Hong KongUpdated: Oct 1, 2025Locations: 1
Eligibility criteria

eyes that received any anti-VEGF therapy in the prior six months, [+2]

Status: Recruiting

Efficacy of SGLT2 Inhibitors in Adults With Sepsis

Goal of this clinical trial is to examine the safety and efficacy of SGLT2 inhibitors on the clinical outcomes in patients with sepsis. Main study outcomes are as follows: (i) Primary objective is to examine the efficacy and safety of SGLT2 inhibitors on clinical outcomes in patients with sepsis. (ii) Secondary objective is to examine the effect of SGLT2 inhibitors on inflammatory markers in patients with sepsis.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Hospital Authority, Hong KongUpdated: Mar 19, 2025Locations: 3
Eligibility criteria

Aged 18 years or above [+4]

Current or recent use of SGLT2 inhibitors (within 12wks prior to randomization) [+7]

Status: Recruiting

Topical Ruxolitinib for Face and Neck Vitiligo of Adult Chinese Patients Refractory to Topical Tacrolimus

This trial is a prospective, open-label, single-center, split face randomized controlled study comparing 1.5% topical Ruxolitinib cream twice daily (BD) to aqueous cream in treating non-segmental vitiligo (NSV) of the face and neck in patient previous failed to respond to topical tacrolimus 0.1%. Aqueous cream twice daily application will be used as control group treatment. Patients with stable NSV at least 0.5% of their total body surface area (BSA) on the face and neck, as determined by the fingertip method, are screened. Recruited subjects will be asked to review their impression of change of their lesion by the end of the study using a 7-point scale.

Participants needed: 20
Trial details
Phase: Phase 2, Phase 3Age: 18-85Biological sex: AllType: InterventionalSponsor: Hospital Authority, Hong KongUpdated: Dec 5, 2024Locations: 1
Eligibility criteria

18 - 85 year old [+6]

Patients who refuse to give consent [+8]