Status: Recruiting
A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
To compare Overall Survival (OS) for INT230-6 vs United States (US) Standard of Care (SOC) in participants with unresectable or metastatic liposarcoma, undifferentiated pleomorphic sarcoma or leiomyosarcoma who have disease progression prior to study enrollment following no more than 2 standard therapies, which must have included an anthracycline-based regimen, unless contraindicated, and then a maximum of 1 additional regimen.
Participants needed: 333
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Intensity Therapeutics, Inc.Updated: Aug 11, 2026Locations: 17
Eligibility criteria
Participant is of any sex and must be ≥ 18 years old and provide written informe... [+14]
Adult participants who lack capacity to consent without a legally authorized rep... [+19]