Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study to Assess Guselkumab in Participants With Moderate-to-Severe Inflammatory Bowel Disease in Real Life Italian Setting

The purpose of this study is to characterize participants with Crohn's Disease (CD) and Ulcerative Colitis (UC) receiving guselkumab in a real-world setting, and to evaluate treatment persistence (continuation) and clinical effectiveness (how well it works) in the overall population and in predefined participant subgroups. The study will also assess patient-reported outcomes, including fatigue (low energy), health-related quality of life (HRQoL), and treatment satisfaction. CD and UC are long-term diseases that cause inflammation in intestine (part of digestive system).

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Janssen-Cilag Ltd.Updated: Oct 1, 2026
Eligibility criteria

The participant must have a confirmed diagnosis of moderate-to-severe CD or UC r... [+2]

The participant is currently enrolled in an interventional clinical study [+3]

Status: Recruiting

A Study of Guselkumab Treatment Persistence in Psoriatic Arthritis Participants

This observational study aims to assess the 1-year persistence of guselkumab in adult patients with psoriatic arthritis (an inflammatory disease that affects the joints in participants with psoriasis, a skin condition that causes red, scaly patches).

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Janssen-Cilag Ltd.Updated: Sep 25, 2026Locations: 1
Eligibility criteria

Have a confirmed diagnosis of psoriatic arthritis (PsA) as determined by a rheum... [+4]

Have already taken a specific interleukin-23 inhibitor (IL-23i) treatment. [+6]

Status: Recruiting

A Study to Observe Real-world Evidence of Guselkumab Treatment in Participants With Ulcerative Colitis and Crohn's Disease in the United Kingdom (UK)

The purpose of this study is to evaluate the clinical effectiveness (how well the treatment works) of Guselkumab, by lines of treatment and subpopulations, and what are the outcomes of treatment (clinical outcomes) in adult participants with moderately to severely active Ulcerative Colitis (UC) or Crohn's Disease (CD) under real-world settings. CD and UC are the main type of Inflammatory bowel disease, a group of inflammatory conditions of the colon and small intestine.

Participants needed: 220
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Janssen-Cilag Ltd.Updated: Sep 25, 2026Locations: 1
Eligibility criteria

Must be eligible for biologic treatment and initiate guselkumab according to the... [+2]

Contraindicated to guselkumab per the label [+4]

Status: Recruiting

A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials

The purpose of this study is to describe the use of teclistamab/talquetamab in the treatment of patients with RRMM outside of clinical trials.

Participants needed: 900
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Janssen-Cilag Ltd.Updated: Aug 28, 2026Locations: 68
Eligibility criteria

Have a documented diagnosis of multiple myeloma [+3]

To be excluded from REALiTEC cohorts if received teclistamab as part of an inter... [+2]