Status: Not yet recruiting
A Study Comparing Oral Ketamine With Oral Midazolam for the Treatment of Major Depressive Episodes
Patients with depression are acutely distressed, often suicidal, and unable to meet the demands of everyday life. If proven effective in a rigorously conducted multicenter randomized controlled trial (RCT), oral ketamine would provide an affordable and scalable, intervention suitable for integration into routine psychiatric services.This study will establish an indigenous, cost-effective therapeutic strategy that could improve accessibility, hasten therapeutic response, and inform treatment guidelines, if found to be safe and effective.
Participants needed: 220
Trial details
Phase: Phase 3Age: 18-65Biological sex: AllType: InterventionalSponsor: Jawaharlal Institute of Postgraduate Medical Education & ResearchUpdated: Oct 1, 2026Locations: 5
Eligibility criteria
Consenting adult outpatients or inpatients with at least moderately severe major...
Patients with co-morbid obsessive-compulsive disorder or intellectual disability...