Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Available

Treatment of Angioedema Attacks in Pediatric (Ages 2-11) Post-Trial and Naive Patients With HAE With Sebetralstat

The sebetralstat Early Access Program (EAP) provides early access to the investigational medicinal product (IMP) sebetralstat to eligible and approved Hereditary Angioedema (HAE) pediatric (ages 2-11) post-trial and naïve patients for the on-demand treatment of angioedema attacks where the treating Physician determines they might benefit from this treatment.

Trial details
Age: 2-11Biological sex: AllType: Expanded AccessSponsor: KalVista Pharmaceuticals, Ltd.Updated: Jul 23, 2026Locations: 6
Eligibility criteria

Male or female patients 2 to 11 years of age. [+2]

Confirmed diagnosis of HAE with nC1-INH or acquired angioedema [+6]

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Status: Not yet recruiting

Safety and Effectiveness of Sebetralstat (KVD900) for Short-Term Prophylaxis Before Procedures in People With Hereditary Angioedema (KONTROL)

This is a Phase 4, prospective, open-label trial to evaluate the safety and effectiveness of sebetralstat when used for STP for a qualifying procedures in patients 12 years of age or older with hereditary angioedema (HAE).

Participants needed: 100
Trial details
Phase: Phase 4Age: 12+Biological sex: AllType: InterventionalSponsor: KalVista Pharmaceuticals, Ltd.Updated: Jul 16, 2026Locations: 1
Eligibility criteria

Male or female patients ≥12 years of age at time of Screening [+8]

A clinically significant history of poor response to bradykinin receptor 2 block... [+8]

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