Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Recruiting

A First-in-human Study of KT502 in Adult Participants With Rheumatoid Arthritis (RA)

This is a Phase 1, open-label, first-in-human study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of KT502 administered subcutaneously to participants with Rheumatoid Arthritis (RA). The study will have 2 parts: Part A is a single ascending dose finding (SAD) and Part B is dose escalation by fractionated dosing.

Participants needed: 27
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Kali Therapeutics, Inc.Updated: Aug 11, 2026Locations: 2
Eligibility criteria

18 to 75 years old [+16]

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Status: Recruiting

A First-in-human Study of KT501 Administered Subcutaneously to Patients With Rheumatoid Arthritis (RA).

This is a Phase 1, open-label, first-in-human study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of KT501 administered subcutaneously to participants with Rheumatoid Arthritis (RA).

Participants needed: 24
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Kali Therapeutics, Inc.Updated: Mar 10, 2026Locations: 1
Eligibility criteria

18 to 75 years old [+6]

Functional class IV as defined by the ACR Classification of Functional Status in... [+9]

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