Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

The purpose of this study is to evaluate the safety, efficacy, tolerability, and pharmacokinetics (PK) of FG-3246, a cluster of differentiation 46 (CD46) targeting antibody-drug conjugate (ADC), in the treatment of participants with mCRPC who have progressed following treatment with one prior second-generation androgen receptor signaling inhibitor (ARSI) in any setting and no prior taxane therapy in the mCRPC setting.

Participants needed: 75
Trial details
Phase: Phase 2Age: 18+Biological sex: MaleType: InterventionalSponsor: Kyntra BioUpdated: Aug 17, 2026Locations: 23
Eligibility criteria

Participant must have histological, and/or cytological confirmation of prostate... [+6]

Participant has received previous treatment with a therapeutic targeting CD46. [+10]

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Status: Not yet recruiting

A Study to Investigate the Efficacy and Safety of Roxadustat (FG-4592) for Treating Anemia in Participants With Myelodysplastic Syndromes (MDS)

The study is designed to determine the efficacy and safety of roxadustat for the treatment of anemia due to very low, low, or intermediate risk MDS in participants with high transfusion burden (HTB).

Participants needed: 201
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Kyntra BioUpdated: Jul 23, 2026
Eligibility criteria

Diagnosis of MDS according to World Health Organization (WHO) criteria confirmed... [+4]

Pregnant or breastfeeding females [+3]

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