Clinical trials

5

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Real-world Study to Assess Adherence to IOP Lowering Therapy in Patients With Glaucoma or Ocular Hypertension Using CONNECTDROP®

The goal of this real-life, national, multicentre, prospective clinical investigation is to describe the adherence rate over time in patients with glaucoma or OHT already treated with IOP-lowering eye drops using connected device CONNECTDROP® The main questions it aims to answer are: * The mean annual adherence rate, defined as the percentage of the prescribed doses taken by the patient * The adherence profile of each patient * The association between the adherence profile, the objective adherence data and the clinical data. Participants will use the connected device CONNECTDROP® associated with the smartphone application on a daily basis.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Laboratoires TheaUpdated: Aug 17, 2026Locations: 15
Eligibility criteria

Adult patient (≥ 18 years old), man or woman [+4]

Pregnant and/or lactating woman [+2]

Status: Recruiting

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

The purpose of this double-masked, randomized, placebo-controlled, paired-eye study is to evaluate the efficacy, safety and tolerability of Sepofarsen in subjects with Leber Congenital Amaurosis (LCA) due to the c.2991+1655A\>G (p.Cys998X) mutation in the CEP290.

Participants needed: 32
Trial details
Phase: Phase 3Age: 6+Biological sex: AllType: InterventionalSponsor: Laboratoires TheaUpdated: Jun 25, 2026Locations: 17
Eligibility criteria

Confirmed clinical diagnosis of LCA10 and a molecular diagnosis of homozygosity... [+4]

Mutations in genes other than the CEP290 gene associated with other IRD diseases... [+4]

Status: Recruiting

Evaluation of Patient Satisfaction With Blephaderm as a Complementary Care in Post-eyelid Surgery

The goal of this non-interventional, open and monocentric study is to evaluate the satisfaction of 30 patients, after 3 months with Blephaderm eyelid cream, as a complementary care in post-eyelid surgery (Blepharopasty or ptosis). The participant will be asked to use Blephaderm twice a day. The patient satisfaction will be evaluated using a VAS scale.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Laboratoires TheaUpdated: May 4, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years old [+3]

Pregnant or nursing woman or planning a pregnancy during the study. [+19]

Status: Recruiting

A Study to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants With Moderate to Severe Vernal Keratoconjunctivitis

The aim of the study is to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants with Moderate to Severe Vernal Keratoconjunctivitis

Participants needed: 120
Trial details
Phase: Phase 2Age: 4-17Biological sex: AllType: InterventionalSponsor: Laboratoires TheaUpdated: Apr 22, 2026Locations: 11
Eligibility criteria

Informed consent signed and dated [+2]

Status: Recruiting

Safety and Efficacy of T10430 Eye Drops in Controlling Paediatric Myopia Progression

Axial myopia is a type of nearsightedness that happens when the eye is too long from front to back. This causes distant vision to be blurry. Axial myopia tends to start during childhood and worsens over time (as the eyes continue to grow longer). This can lead to serious eye-related conditions later in life. The aim of T10430 treatment is to stop or slow this progression during childhood and therefore, prevent more serious complications. Animal studies using drugs with a similar mechanism of action as T10430 have demonstrated positive safety results. This study aims to better understand the safety and potential effectiveness of T10430 in children with axial myopia.

Participants needed: 200
Trial details
Phase: Phase 2Age: 6-11Biological sex: AllType: InterventionalSponsor: Laboratoires TheaUpdated: Apr 13, 2026Locations: 10
Eligibility criteria

- Informed consent signed and dated. [+4]

Known intolerance to administration of eye drops. [+10]