Clinical trials

5

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Aphasia

The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with aphasia to generate text on a computer screen and audible, computer-generated speech by attempting to speak.

Participants needed: 5
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Leigh R. Hochberg, MD, PhD.Updated: Aug 31, 2026
Eligibility criteria

Clinical diagnosis of expressive aphasia due to ischemic or hemorrhagic stroke (...

Visual impairment such that extended viewing of a computer monitor would be diff... [+2]

Status: Recruiting

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

People with brainstem stroke, advanced amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), or other disorders can become unable to move or speak despite being awake and alert. In this project, the investigators seek to further translate knowledge about interpreting brain signals related to movement, and to further develop an intracortical brain-computer interface (iBCI) that could restore rapid and intuitive use of communication apps on tablet computers by people with paralysis.

Participants needed: 6
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Leigh R. Hochberg, MD, PhD.Updated: Jun 25, 2026Locations: 1
Eligibility criteria

Clinical diagnosis of spinal cord injury, brainstem stroke, muscular dystrophy,... [+3]

Visual impairment such that extended viewing of a computer monitor would be diff... [+2]

Status: Recruiting

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts.

Participants needed: 3
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Leigh R. Hochberg, MD, PhD.Updated: Jun 2, 2026Locations: 2
Eligibility criteria

Between 18 and 80 years of age. [+3]

Visual impairment such that extended viewing of a computer monitor would be diff... [+2]

Status: Recruiting

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts.

Participants needed: 27
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Leigh R. Hochberg, MD, PhD.Updated: Jun 1, 2026Locations: 6
Eligibility criteria

Clinical diagnosis of spinal cord injury, brainstem stroke, muscular dystrophy,... [+3]

Visual impairment such that extended viewing of a computer monitor would be diff... [+3]

Status: Recruiting

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)

The goal of this study is to improve our understanding of speech production, and to translate this into medical devices called intracortical brain-computer interfaces (iBCIs) that will enable people who have lost the ability to speak fluently to communicate via a computer just by trying to speak.

Participants needed: 2
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Leigh R. Hochberg, MD, PhD.Updated: Dec 1, 2025Locations: 1
Eligibility criteria

Between 18 and 80 years of age [+3]

Visual impairment such that extended viewing of a computer monitor would be diff... [+2]