Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effects of Alternating Altitude Training Versus Fixed-Altitude Training on Exercise Capacity and Physiological Adaptations in Elite Race Walkers: A Randomized Controlled Trial

This randomized controlled trial aims to compare the effects of alternating altitude training and fixed-altitude training on physical performance and physiological adaptations in elite race walkers living at altitude. Elite race walkers from Yunnan Province will be randomly assigned to either an alternating altitude training group or a fixed-altitude training group. The alternating altitude training group will perform selected training sessions under simulated higher-altitude conditions while completing the remaining sessions at their regular altitude training base. The fixed-altitude training group will complete all training sessions at the regular altitude. Physical performance, race walking performance, cardiovascular function, pulmonary function, and hematological parameters will be assessed before and after the intervention to evaluate the effectiveness of the two altitude training strategies.

Participants needed: 16
Trial details
Age: 18-26Biological sex: MaleType: InterventionalSponsor: Macao Polytechnic UniversityUpdated: Jul 21, 2026Locations: 1
Eligibility criteria

Male and female elite race walkers aged 16-26 years. Registered athletes from th...

Any cardiovascular, respiratory, metabolic, neurological, or other medical condi...

Status: Recruiting

Effects of a 4-Week Altitude Training on Sport-Specific Performance, Body Composition, and Cardiac and Pulmonary Function in Adolescent Male Rowers

This study aims to investigate the effects of a 4-week altitude training program on adolescent male rowers. The research will examine changes in athletic performance, athletic body composition, athletic cardiac function, athletic pulmonary function, and selected blood markers. Participants will be stratified by biological maturation based on peak height velocity to explore whether maturity influences athletic training adaptations. Measurements will include non-invasive assessments of athletic performance, athletic body composition, athletic heart and lung function, as well as venous blood sampling for hematological markers. The study intends to provide evidence for optimizing high-altitude training strategies in youth rowing.

Participants needed: 20
Trial details
Age: 12-19Biological sex: MaleType: InterventionalSponsor: Macao Polytechnic UniversityUpdated: May 29, 2026Locations: 1
Eligibility criteria

Not listed

Status: Recruiting

Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training

This randomized controlled trial investigates the effects of hot spring balneotherapy on central fatigue elimination in adolescent rowers undergoing altitude training at approximately 1600 meters (Tengchong, Yunnan). Thirty adolescent athletes (aged 12-16 years) will be stratified by sex and randomly allocated to three groups: Group A (natural recovery, no immersion), Group B (38°C pure water immersion), and Group C (38°C sodium bicarbonate hot spring immersion). Interventions will be administered 3 times per week for 4 weeks. The primary outcomes are central fatigue indices including voluntary activation (VA) and central activation ratio (CAR). Secondary outcomes encompass cognitive function (Stroop test, Psychomotor Vigilance Test), cerebral hemodynamics (functional near-infrared spectroscopy, transcranial Doppler ultrasound), exercise performance (maximal oxygen uptake, 1000m test, 500m test), blood lactate, and hematological parameters (white blood cells, neutrophils, platelets).

Participants needed: 27
Trial details
Age: 12-16Biological sex: AllType: InterventionalSponsor: Macao Polytechnic UniversityUpdated: May 29, 2026Locations: 1
Eligibility criteria

Male or female aged 12-16 years- Healthy with no serious chronic diseases or ski... [+4]

History of cardiovascular, respiratory, renal, endocrine, or neurological disord... [+5]