Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Restoring Sinus Rhythm Using Dual-Shock Technique in Patients With Atrial Fibrillation

The goal of this clinical trial is to assess the efficacy and acute safety of the dual electrical cardioversion (ECV) technique compared with the conventional ECV in patients with persistent atrial fibrillation. The main question it aims to answer are: * Is dual ECV more effective than conventional ECV to achieve sinus rhythm restoration? * Is dual ECV safe compared with conventional ECV? * Which are the main factors associated with cardioversion success? Researchers will compare a dual ECV technique with 400J with dual ECV with 200J and conventional ECV. Participants will be randomized to one ECV configuration. The primary efficacy endpoint will be considered the percentage of patients with successful cardioversion with the first shock. The coprimary safety endpoint will be the occurrence of adverse events during ECV.

Participants needed: 177
Trial details
Phase: Phase 2, Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Martín Negreira Caamaño, MD, PhDUpdated: Jul 28, 2026
Eligibility criteria

Diagnosis of persistent AF. [+2]

Long-standing persistent atrial fibrillation (more than 1 year of uninterrupted... [+4]