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Condition / disease
Location
Status: Not yet recruiting

Broadband Near Infrared Spectroscopy to Understand the Role of Brain Cytochrome C Oxidase in Bipolar Disorder

People with a diagnosis of bipolar disorder who are depressed will have a light-based imaging of the brain (Near Infrared Spectroscopy) before and after they have treatment for their depression with a standard, approved medication named lurasidone. They will also answer questions about their history, and give blood samples. The goal is to understand the role of mitochondrial activity in bipolar disorder. Healthy volunteers who have never had a psychiatric disorder will have the same procedures, but they will not receive the medication.

Participants needed: 60
Trial details
Phase: Phase 4Age: 18-60Biological sex: AllType: InterventionalSponsor: Martin LanUpdated: Sep 8, 2026Locations: 1
Eligibility criteria

Diagnosis of bipolar disorder [+2]

Taking any medications that cannot be combined with lurasidone [+6]