Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of MZE782 in Adults With PKU

The purpose of this study is to evaluate the safety, tolerability, and efficacy of MZE782 in adults with Phenylketonuria (PKU).

Participants needed: 38
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Maze TherapeuticsUpdated: Aug 20, 2026Locations: 6
Eligibility criteria

Males and females 18 to 75 years old [+5]

Is pregnant, breastfeeding, or planning to become pregnant or conceive a child d... [+3]

Status: Recruiting

A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

The purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease.

Participants needed: 74
Trial details
Phase: Phase 2Age: 18-68Biological sex: AllType: InterventionalSponsor: Maze TherapeuticsUpdated: Jul 27, 2026Locations: 79
Eligibility criteria

APOL1 high risk genotype of G1/G1, G2/G2, or G1/G2 [+1]

Organ or bone marrow transplantation [+4]