Health TrialsbyHealthPanel

Clinical trials

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Condition / disease
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Status: Not yet recruiting

A Multicenter, Prospective, Randomized, Placebo and Non-Surgical Standard of Care (NSSOC) Controlled Study, Performed to Evaluate the Safety and Efficacy of EscharEx and Its Placebo (Gel Vehicle) Compared to NSSOC in Participants With Venous Leg Ulcers (VLU)

The objectives of this study are: * To evaluate the safety of EscharEx and its placebo Gel Vehicle compared to non-surgical standard of care (NSSOC) * To assess the efficacy of EscharEx (EX-03 5% formulation) compared to placebo control and compared to NSSOC.

Participants needed: 45
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: MediWound LtdUpdated: Oct 13, 2026Locations: 2
Eligibility criteria

Men or women, older than 18 years of age, [+5]

Wound size decreased by >20% after 7 (+3/-1) days of the screening period, [+24]

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Status: Recruiting

A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)

The main objective of this study is: To assess the efficacy and safety of EscharEx (EX-03 5% formulation) compared to placebo control,in debridement and wound bed preparation of Venous Leg Ulcers (VLU).

Participants needed: 216
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: MediWound LtdUpdated: Oct 9, 2026Locations: 60
Eligibility criteria

Men or women, older than 18 years of age, [+5]

Wound size that has decreased by > 20% after 7 (+3/-1) days of the screening per... [+24]

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Status: Not yet recruiting

An Open Label, Single Treatment, Single Arm, Multiple Dose Phase-2 Study to Evaluate the Pharmacokinetics, Safety, and Clinical Performance of EscharEx (EX-03) in Participants With Venous Leg Ulcers

This is a pharmacokinetics (PK) study - the main objective of this study is to assess the PK, safety and clinical performance of 5% EscharEx (EX-03 formulation) in debridement of Venous Leg Ulcers

Participants needed: 20
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: MediWound LtdUpdated: Jul 9, 2026
Eligibility criteria

Men or women, older than 18 years of age, [+5]

Wound size that has decreased by > 20% after 7 (+3/-1) days of the screening per... [+24]

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Status: Recruiting

A Study to Evaluate the Safety and Efficacy of EscharEx (EX-02) in the Treatment of Basal Cell Carcinoma

This study will be a multicenter, prospective, open label, one-arm study intended to assess the Safety and Efficacy of EscharEx (EX-02) in the treatment of Basal Cell Carcinoma. In patients with one primary superficial or nodular basal cell carcinoma lesion with a diameter of 5-10mm (Histologically confirmed BCC) located on the trunk or upper extremities (not including the hands), with well-defined borders and no previous radiation therapy.

Participants needed: 32
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: MediWound LtdUpdated: Dec 15, 2021Locations: 3
Eligibility criteria

Male or female greater than age 18, [+4]

Evidence of Gorlin syndrome, neoplastic diseases (except actinic lesions), metas... [+11]

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