Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Real-world Patient Experiences With Inbrija®

Parkinson's disease can cause OFF episodes, when medication effects wear off and symptoms return, affecting movement, daily activities, comfort, and wellbeing. This study aims to explore the experiences of people with Parkinson's disease who are prescribed Inbrija® as part of their usual care. Through a mixed-methods approach, the study will examine how OFF episodes affect patients, what influences their decision to use Inbrija®, and whether patient-reported outcomes related to symptoms, daily functioning, and quality of life change during the first 3 months of treatment. The study is planned to be conducted at approximately 7 sites in Austria, Germany, and Sweden and will enroll up to 120 participants receiving Inbrija® in routine clinical practice.

Participants needed: 120
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Merz Therapeutics GmbHUpdated: Oct 2, 2026Locations: 2
Eligibility criteria

Adults aged 18 years or older. [+5]

Previous use of Inbrija® before study enrollment. [+6]

Status: Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections. Trial details include: * Trial duration: 52 to 55 weeks; * Screening period: 4 to 5 weeks; * Treatment duration: 4 treatments, each about 12 weeks apart; and * Visit frequency: about every 4 weeks, 14 visits in total. The first and last visit and the 4 treatment visits are on-site, the other 8 visits are remote by phone / video call.

Participants needed: 780
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Merz Therapeutics GmbHUpdated: Sep 25, 2026Locations: 111
Eligibility criteria

Participant has a diagnosis of CM with or without aura according to the Internat... [+3]

Diagnosis of other primary headache types, except tension-type headache, which i... [+4]

Status: Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine

In this clinical trial, participants with episodic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections. Trial details include: * Trial duration: 52 to 55 weeks; * Screening period: 4 to 5 weeks; * Treatment duration: 4 treatments, each about 12 weeks apart; and * Visit frequency: about every 4 weeks, 14 visits in total. The first and last visit and the 4 treatment visits are on-site, the other 8 visits are remote by phone / video call.

Participants needed: 990
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Merz Therapeutics GmbHUpdated: Sep 25, 2026Locations: 110
Eligibility criteria

Participant has a diagnosis of EM with or without aura according to current Inte... [+3]

Diagnosis of chronic migraine; [+5]