Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Regulated Stimulation for Optimized Network Activity and Therapeutic Equilibrium

The objective of this study is to evaluate the safety, tolerability, and preliminary efficacy of the Motif eXternally powered Cortical Stimulation (XCS) System when used as indicated for treatment-resistant depression (TRD).

Participants needed: 20
Trial details
Age: 22-85Biological sex: AllType: InterventionalSponsor: Motif Neurotech, Inc.Updated: Sep 29, 2026Locations: 2
Eligibility criteria

Has a diagnosis of unipolar non-psychotic Major Depressive Disorder (MDD) and is... [+6]

Has a cranial implant (with the exception of dental implants), neurostimulator,... [+23]

Status: Not yet recruiting

Regulated Stimulation for Optimized Network Activity and Therapeutic Equilibrium - Maintenance

The objective of this study is to evaluate the safety, tolerability, and preliminary efficacy of the Motif XCS System when used as indicated for treatment-resistant depression (TRD).

Participants needed: 10
Trial details
Age: 22-85Biological sex: AllType: InterventionalSponsor: Motif Neurotech, Inc.Updated: Jul 6, 2026
Eligibility criteria

Has a diagnosis of unipolar non-psychotic Major Depressive Disorder (MDD) and is... [+6]

Has a cranial implant (with the exception of dental implants), neurostimulator,... [+23]