Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Safety and Efficacy Study of OMS906 in Patients With C3G and ICGN

The purpose of this study is to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of OMS906 in patients with C3 Glomerulopathy (C3G) and Idiopathic Immune Complex-Mediated Glomerulonephritis (ICGN)

Participants needed: 20
Trial details
Phase: Phase 2Age: 18-99Biological sex: AllType: InterventionalSponsor: Omeros CorporationUpdated: Jul 15, 2025Locations: 6
Eligibility criteria

Male or female adults 18 years and older. [+12]

History of major organ transplant or hematopoietic stem cell/marrow transplant. [+18]

Status: Recruiting

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following hematopoietic stem cell transplant (HSCT).

Participants needed: 18
Trial details
Phase: Phase 2Age: 28-17Biological sex: AllType: InterventionalSponsor: Omeros CorporationUpdated: Mar 25, 2025Locations: 16
Eligibility criteria

Age at least 28 days and less than 18 years prior to informed consent (Visit 0). [+16]

All treatments for HSCT-TMA are allowed except eculizumab, ravulizumab, and defi... [+12]