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Condition / disease
Location
Status: Recruiting

HME Amino Acid Supplementation for Strength, Performance, and Recovery in Trained Adult Males

This pilot randomized controlled trial evaluates HME (Human Muscle Equivalent), a free-form amino acid supplement formulated to match the amino acid composition of human skeletal muscle, taken at its Health Canada licensed dose (3 g powder plus one 50 mg slow-release beta-alanine capsule daily). Trained adult males (competitive athletes or certified fitness professionals) are randomized to HME or an identical-appearing placebo for 10 weeks: a 2-week supplement-only lead-in followed by 8 weeks of supplement plus supervised resistance training. The primary aim is to estimate the effect of HME on composite maximal strength (1-repetition maximum leg press plus chest press) compared with placebo. Secondary measures include isometric knee-extension strength, countermovement jump height, and subjective recovery.

Participants needed: 50
Trial details
Age: 18-45Biological sex: MaleType: InterventionalSponsor: Orivian incUpdated: Jul 23, 2026Locations: 1
Eligibility criteria

Age 18 to 45 years inclusive [+8]

Use of anabolic steroids, SARMs, prohormones, or beta-alanine supplements (other... [+6]