Health TrialsbyHealthPanel

Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

ORKA-002 Versus Placebo in Participants With Moderate-to-Severe Hidradenitis Suppurativa

This is a multicenter, randomized, double-blinded, placebo-controlled clinical study of ORKA-002 in adult participants with moderate-to-severe HS.

Participants needed: 200
Trial details
Phase: Phase 2Age: 18-79Biological sex: AllType: InterventionalSponsor: Oruka Therapeutics, Inc.Updated: Sep 24, 2026Locations: 15
Eligibility criteria

Has signs and symptoms of HS for at least 6 months; [+2]

Presence of any other active skin disease or condition that may interfere with t... [+1]

Read more
Status: Recruiting

An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

An open-label extension (OLE) study to evaluate the long-term safety and efficacy of ORKA-001 in adult participants with moderate-to-severe plaque psoriasis, who previously participated in an Oruka Therapeutics sponsored study.

Participants needed: 240
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Oruka Therapeutics, Inc.Updated: Sep 23, 2026Locations: 34
Eligibility criteria

Signed informed consent by participants from previous trial choosing to transiti... [+3]

Participants who experienced any adverse events with ORKA-001 in the preceding t... [+4]

Read more
Status: Recruiting

Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

This is a multicenter, randomized, double-blinded, placebo-controlled, dose-range finding study to evaluate the efficacy and safety of ORKA-002 in adult participants with moderate-to-severe plaque psoriasis.

Participants needed: 160
Trial details
Phase: Phase 2Age: 18-79Biological sex: AllType: InterventionalSponsor: Oruka Therapeutics, Inc.Updated: Aug 10, 2026Locations: 39
Eligibility criteria

Participants ≥ 18 and < 80 years of age at the time of consent [+6]

Nonplaque forms of psoriasis (including guttate, erythrodermic, or pustular) or... [+4]

Read more