Health Trials

Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

The primary objective of this study is to collect and evaluate clinical evidence supporting the safety and performance of the Indigo™ Aspiration System in a patient population with lower extremity acute limb ischemia (LE ALI).

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Penumbra Inc.Updated: Aug 7, 2026Locations: 42
Eligibility criteria

Age ≥18 years [+6]

Life expectancy <1 year [+11]

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Status: Recruiting

FORWARD: Functional Outcomes in Real-World Treatment And Revascularization of Non-dominant and Distal M2 Occlusions

The objective of this study is to collect safety and effectiveness data on the Penumbra System reperfusion catheters in participants with isolated primary non-dominant and distal M2 occlusions who undergo endovascular mechanical thrombectomy (EVT). Additionally, this study aims to observe characteristics and outcomes of participants treated with medical management (MM) alone and those who receive EVT + MM per current medical practice.

Participants needed: 250
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Penumbra Inc.Updated: Aug 6, 2026Locations: 1
Eligibility criteria

Participant age ≥ 18 [+5]

Any stenosis or occlusion in the ICA origin requiring treatment during the proce... [+6]

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Status: Recruiting

Study to Collect Real-world Performance and Safety Data on Penumbra System® in Population With Acute Ischemic Stroke (AIS).

The primary objective of this study is to collect real-world performance and safety data on the Penumbra System in a patient population with acute ischemic stroke (AIS)

Participants needed: 200
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Penumbra Inc.Updated: Jul 27, 2026Locations: 10
Eligibility criteria

I.1. Patient age 18-80 years [+4]

E.1. Alberta Stroke Program Early CT Score (ASPECTS) ≤6 (for anterior circulatio... [+4]

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Status: Recruiting

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

The objective of this study is to evaluate real world long-term functional outcomes, safety and performance of the Indigo Aspiration System for the treatment of pulmonary embolism (PE).

Participants needed: 1,500
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Penumbra Inc.Updated: Jul 6, 2026Locations: 79
Eligibility criteria

Clinical signs and symptoms consistent with acute PE with duration of 14 days or... [+4]

Contraindication to systemic or therapeutic doses of anticoagulants (e.g. hepari... [+7]

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