Health TrialsbyHealthPanel

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant Soft Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency

This is a Phase 3, multicenter, 3-part study, with 2 randomized, double-blind, placebo-controlled parts and an open-label extension part, to evaluate the efficacy and safety of orally administered deucrictibant XR tablet for prophylaxis, and deucrictibant soft capsule for on-demand treatment of angioedema attacks in adult participants aged ≥ 18 years with AAE-C1INH.

Participants needed: 48
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Pharvaris Netherlands B.V.Updated: Sep 21, 2026Locations: 32
Eligibility criteria

Provision of written informed consent [+6]

Participation in a clinical study with any other investigational drug within the... [+11]

Read more
Status: Available

EAP for Deucrictibant Immediate-release

This is an expanded access program (EAP) designed to allow access to deucrictibant immediate-release (IR) capsule for eligible participants with hereditary angioedema (HAE) in the United States (US) and US territories who lack satisfactory alternative treatment options for on-demand treatment of HAE attacks, as determined by their treating physician.

Trial details
Age: 12-75Biological sex: AllType: Expanded AccessSponsor: Pharvaris Netherlands B.V.Updated: Aug 12, 2026
Eligibility criteria

Provision of informed consent: Participants must provide written informed consen... [+9]

Pregnancy or nursing: any female participant who is pregnant, planning to become... [+8]

Read more