Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg Compared to Placebo for Relief of Episodic Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease Through 24 Weeks

The main objective is to assess the efficacy of vonoprazan (10 mg as needed) compared to placebo (as needed) in relief of episodic heartburn at 2 hours that is sustained for 24 hours over 12 weeks of treatment in participants with non-erosive gastroesophageal reflux disease (GERD).

Participants needed: 500
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Phathom Pharmaceuticals, Inc.Updated: Aug 7, 2026
Eligibility criteria

The participant is ≥18 years of age at the time of informed consent signing. [+10]

The participant has endoscopically confirmed erosive esophagitis (EE) during the... [+25]

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Status: Recruiting

A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring

The main objective of the study is to compare the maternal, fetal, and infant outcomes of pregnant women who are exposed to vonoprazan during pregnancy with outcomes of an internal comparison cohort of pregnant women who are unexposed to vonoprazan during pregnancy but who may be exposed to other products for the treatment of conditions for which vonoprazan may be prescribed.

Participants needed: 728
Trial details
Age: 15-50Biological sex: FemaleType: ObservationalSponsor: Phathom Pharmaceuticals, Inc.Updated: May 22, 2025Locations: 1Duration: 12 Months
Eligibility criteria

Women 15 to 50 years of age. [+5]

Occurrence of pregnancy outcome prior to first contact with the virtual research... [+2]

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