Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

A Multi-Center, Single-Arm Clinical Trial to Investigate the Efficacy and Safety of Elsunersen in Pediatric Participants with Early Onset SCN2A Developmental and Epileptic Encephalopathy

Participants needed: 40
Trial details
Phase: Phase 3Age: 1-18Biological sex: AllType: InterventionalSponsor: Praxis Precision MedicinesUpdated: Aug 3, 2026Locations: 10
Eligibility criteria

Has a documented Gain of Function SCN2A variant confirmed through genetic testin... [+2]

Has any clinically significant or known pathogenic genetic variant other than in... [+3]

Status: Recruiting

An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures

An Open Label Clinical Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adult Patients With Focal Onset or Primary Generalized Tonic-Clonic Seizures

Participants needed: 50
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Praxis Precision MedicinesUpdated: Apr 3, 2025Locations: 11
Eligibility criteria

A diagnosis of focal onset seizures or idiopathic generalized tonic clonic seizu... [+3]

History of pseudo or psychogenic seizures, or cluster seizures only, within the... [+10]