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Status: Recruiting

Phase 1a Study Assessing Safety, Tolerability, Pharmacokinetics, and Immunogenicity of PMG1016

This study is a first-in-human (FIH), randomized, double-blind, placebo-controlled study of PMG1016 in healthy adult participants. It aims to investigate the safety, tolerability, PK, and immunogenicity of PMG1016 administered via IV infusion. Cohort 1: Healthy participants receiving single doses of PMG1016 Dose 1 or placebo. Cohort 2: Healthy participants receiving single doses of PMG1016 Dose 2 or placebo. Cohort 3: Healthy participants receiving single doses of PMG1016 Dose 3 or placebo. Cohort 4: Healthy participants receiving single doses of PMG1016 Dose 4 or placebo.

Participants needed: 30
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Pulmongene Ltd.Updated: Sep 23, 2026Locations: 1
Eligibility criteria

Participants must be in good health based on medical history, physical exam, vit... [+4]

History or evidence of any clinically significant medical condition (e.g., cardi... [+20]