Clinical trials

Generative artificial intelligence (GenAI) tools are increasingly used by medical students for literature searching, scientific writing, and research. However, AI-generated citations may contain errors. Some references may not exist or may contain incorrect bibliographic details, while other references may be genuine but may not actually support the claim for which they are cited. This randomized educational study will evaluate whether a structured citation-verification framework called SARA can improve medical students' ability to identify and correct these problems. SARA teaches students to assess four elements of a citation: Source authenticity, Accuracy, Relevance, and Alignment between the cited evidence and the claim being made. Year 3-5 medical students will be randomly assigned to either a 75-minute SARA training session or an attention-matched session on responsible use of GenAI in academic work. Participants will complete citation-verification assessments before training, immediately after training, and 12 weeks later. The main outcome will assess whether students can independently apply the verification approach to an unstructured literature-review task 12 weeks after training, without being prompted to use SARA. The study will also examine which types of citation errors remain difficult, whether students initiate appropriate verification, the quality of their verification, handling of valid citations, and confidence in their judgments. A subgroup of participants will take part in think-aloud and follow-up interviews to explore how they approach citation verification and transfer the strategy to new tasks.

Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting reproductive-aged women and is associated with menstrual irregularities, infertility, hyperandrogenism, obesity, and insulin resistance. Myo-inositol is commonly used as an insulin-sensitizing agent to improve reproductive and metabolic outcomes in women with PCOS. Alpha-lactalbumin may enhance the intestinal absorption and bioavailability of myo-inositol and potentially improve treatment response. This randomized controlled trial aims to compare the efficacy of myo-inositol alone versus myo-inositol plus alpha-lactalbumin in women with PCOS. Eighty-two eligible women will be randomized to receive either myo-inositol alone or myo-inositol combined with alpha-lactalbumin for 12 weeks. The study will evaluate reproductive outcomes including spontaneous conception, menstrual regularity, hirsutism, and hormonal parameters, as well as metabolic outcomes including body mass index and insulin resistance.

Study will evaluate effects of oral zinc and probiotics supplementation in neonates who have indirect hyperbilirubinemia and are receiving phototherapy. Aim is to compare efficacy of these two drugs in clearing bilirubin and reducing duration of phototherapy. Neonates will be randomly assigned to receive either drug alongside phototherapy.