Clinical trials

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Condition / disease
Location
Status: Recruiting

Cardiac Output and Fatigue in Friedreich's Ataxia

This is a clinical trial examining to impact of aerobic training plus omaveloxolone in FRDA. Thirty individuals with FRDA will be recruited; 20 individuals will be on omaveloxolone treatment whereas the other ten individuals will not. Individuals will undergo baseline assessment including cardiopulmonary exercise testing (CPET), mFARS, gait speed, Timed Up and Go (TUG), Fatigue Severity Scale (FSS), Fatigue Impact Scale (FIS), and 6-minute Walk Test (6MWT). Individuals will then perform 3-months of home aerobic training. Repeat assessments will be conducted at 3- and 6-months.

Participants needed: 30
Trial details
Biological sex: AllType: InterventionalSponsor: Scott BarbutoUpdated: Sep 22, 2026Locations: 1
Eligibility criteria

Genetically confirmed FRDA [+1]

Beck depression score >19, a score that precludes ability to exercise. [+4]