Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

First in Human Study of SNV1521 With a RAS Inhibitor for People With Advanced Pancreatic Cancer

This study is a Phase 1 clinical trial testing an oral investigational drug called SNV1521 together with a RAS-targeted cancer medicine in people with pancreatic cancer that cannot be removed by surgery or has spread. The main goals are to find doses of the drug combination that are safe and tolerable and to look for early signs that the treatment may help control the cancer. Participants will receive the study medicines in repeating cycles and will have regular blood tests, scans, and other exams to monitor side effects and how their cancer responds.

Participants needed: 40
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Synnovation Therapeutics, Inc.Updated: Aug 10, 2026
Eligibility criteria

Adults (18 years and older). [+6]

Serious heart, lung, liver, or other medical problems that would make study trea... [+5]

Status: Recruiting

SNV1521 in Participants With Advanced Solid Tumors

This study is testing a new medicine, SNV1521, for people with advanced cancers. The researchers want to find out if SNV1521 is safe, well-tolerated, and effective in treating solid tumors. They are investigating different doses in order to find the most effective and safe one. They are also investigating whether it can be combined with other cancer therapies.

Participants needed: 400
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Synnovation Therapeutics, Inc.Updated: Jun 25, 2026Locations: 25
Eligibility criteria

Advanced or metastatic solid tumor malignancy [+3]

History of other malignancy within the past 2 years [+5]