Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Pericapsular Nerve Group Block Versus Femoral Nerve Block Study

Hip fractures are common in older adults and are often associated with severe pain, making it difficult for patients to sit for spinal anesthesia before surgery. Peripheral nerve blocks may improve pain control and facilitate patient positioning, but it remains uncertain whether the Pericapsular Nerve Group (PENG) block provides advantages over the traditional femoral nerve block during the spinal anesthesia procedure.

Participants needed: 110
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: Taksim Egitim ve Arastirma HastanesiUpdated: Jul 31, 2026Locations: 2
Eligibility criteria

Adults aged 50 years or older. [+4]

Refusal to participate or inability to provide informed consent. [+9]

Status: Not yet recruiting

Erector Spinae Plane Block Versus Infraspinatus-Teres Minor Interfascial Plane Block for Analgesia After Shoulder Arthroscopy

The shoulder, being an anatomical region innervated by different nerves, has a wide variety of analgesic approaches, which differ depending on the practitioner. New approaches are being developed based on the different innervation channels demonstrated in clinical and cadaver studies. Over time, the effectiveness of axillary block, suprascapular block, interscalene block, local infiltration, and various combinations, as well as non-regional methods, has been observed. The goal of these approaches is to achieve the highest possible level of patient comfort, high analgesic efficacy, and minimal complications. Studies have shown that the interscalene block has the highest analgesic efficacy and the most ideal postoperative results; therefore, it is frequently used as the gold standard in this field. Providing effective analgesia with a single intervention can also be cited as an aspect that increases patient comfort and simplifies the procedure. In interscalene block; unilateral transient diaphragmatic paralysis due to the spread of local anesthetics to the C7 nerve root, respiratory problems and potential spinal/epidural complications, new approaches are being followed and researched. Results from cervical/high thoracic erector spinae plane block (ESPB) and infraspinatus-teres minor interfascial plane block (ITMIPB) studies, which are the subject of new studies, strengthen the hypothesis that they provide effective analgesia. Neither of these blocks, performed with ultrasonography, carries the risks present in interscalene block. Although the usual risks of a peripheral nerve block are present for these procedures; the block sites are considered safer due to its distance from vascular structures and the reduced risk of additional complications. While small sample studies exist for each type of block, no studies comparing their effectiveness have been found. Besides reduced complications, another advantage of these two blocks is their ability to provide effective analgesia with a single-point injection. The aim of this study is to compare the analgesic efficacy of Cervical Erector Spine Plane Block (ESP) and Infraspinatus-Teres Minor Interfascial Plane Block (ITMIPB) applied for postoperative analgesia in ASA I-III patients undergoing shoulder surgery.

Participants needed: 100
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Taksim Egitim ve Arastirma HastanesiUpdated: Jul 7, 2026Locations: 1
Eligibility criteria

Adults scheduled for elective shoulder arthroscopy [+2]

Patients with previously known allergy to local anesthetics. [+5]

Status: Recruiting

Non-Pharmacological Factors on Spinal Block Duration

The aim of this study is to evaluate the effects of non-pharmacological factors-such as age, sex, body mass index, paraspinal muscle mass, vertebral canal anatomy, patient positioning, and injection technique-on the duration of sensory and motor block in patients undergoing spinal anesthesia, and to investigate the potential relationships between these factors and block duration.

Participants needed: 140
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Taksim Egitim ve Arastirma HastanesiUpdated: Jun 23, 2026Locations: 1
Eligibility criteria

Patients aged 18-80 years [+2]

Patient refusal to participate [+10]

Status: Recruiting

Erector Spinae Plane Block and Low-Flow Anaesthesia in Laparoscopic Cholecystectomy

This prospective randomized controlled study aims to evaluate the effects of preoperative ultrasound-guided erector spinae plane (ESP) block combined with low-flow anaesthesia on postoperative quality of recovery and opioid consumption in patients undergoing elective laparoscopic cholecystectomy. The study will compare postoperative recovery quality, pain scores, analgesic requirements, and perioperative outcomes between patients receiving ESP block with low-flow anaesthesia and those receiving standard anaesthetic management.

Participants needed: 72
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Taksim Egitim ve Arastirma HastanesiUpdated: Jun 23, 2026Locations: 1
Eligibility criteria

Patients aged 18-65 years [+4]

Coagulopathy or bleeding disorders [+12]