Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Phase 1b Study of TX002100 in Participants With Hematologic Support-Dependent Hereditary Hemorrhagic Telangiectasia (HHT)

The primary purpose of this study is to assess the safety and tolerability of TX002100 in participants with hereditary hemorrhagic telangiectasia (HHT). The study will also look at whether TX002100 reduces the need for blood or iron treatments, and whether it improves blood counts, such as hemoglobin levels.

Participants needed: 20
Trial details
Phase: Phase 1Age: 18-80Biological sex: AllType: InterventionalSponsor: Tectonic Operating Company, Inc.Updated: Oct 7, 2026
Eligibility criteria

Adults with HHT who need regular intravenous iron or blood transfusions. [+2]

History of anemia of any cause other than HHT-related bleeding, or any other cli... [+6]

Status: Recruiting

Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease

The primary purpose of this study is to assess the effect of TX000045 on pulmonary vascular resistance (PVR) in participants with pulmonary hypertension secondary to interstitial lung disease (PH-ILD) and to assess the safety and tolerability of TX000045 in participants with PH-ILD.

Participants needed: 25
Trial details
Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: Tectonic Operating Company, Inc.Updated: Sep 8, 2026Locations: 16
Eligibility criteria

Confirmed diagnosis of ILD based on imaging: chest computed tomography (CT) perf... [+2]

Participants have a confirmed or suspected diagnosis of pulmonary hypertension i... [+3]