Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type

The primary objective of this study is to evaluate the efficacy of DMTS on frequency and severity of agitation associated with dementia of the Alzheimer's type, compared with placebo.

Participants needed: 150
Trial details
Phase: Phase 2Biological sex: AllType: InterventionalSponsor: Teikoku Pharma USA, Inc.Updated: Oct 8, 2026Locations: 10
Eligibility criteria

Voluntarily provide written informed consent (subject or legally authorized repr... [+12]

Has a known sensitivity to dexmedetomidine or any excipient in the DMTS/placebo. [+21]

Status: Not yet recruiting

A Repeat Dose Study of the Dexmedetomidine Transdermal System in Healthy Subjects

This Phase 1, 16-day Repeat dose study will evaluate the safety of a Dexmedetomidine Transdermal System (DMTS) skin system in healthy adults Subjects. Participants will receive the patch for four consecutive 4-day treatment periods. Researchers will monitor safety, drug levels in the blood, sedation effects, skin irritation, and how well the patch stays attached to the skin.

Participants needed: 20
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Teikoku Pharma USA, Inc.Updated: Sep 14, 2026
Eligibility criteria

Subjects must be non-smokers, as defined by cessation of smoking and consumption... [+5]

History of allergy or hypersensitivity to dexmedetomidine or dexmedetomidine hyd... [+7]