Clinical trials

5

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

The Effect of a Postbiotic on Oral Health in Healthy Adults

The goal of this randomised, placebo-controlled trial is to determine the effect of a chewable postbiotic tablet on the oral health of male and female healthy adults under conditions of short term oral-neglect (a short, temporary period during which participants do not perform their usual oral hygiene practices, such as tooth brushing and flossing). The main questions the study aims to answer are: 1. Does postbiotic ingestion impact dental plaque accumulation, gingival (gum) inflammation, and periodontal health compared with placebo? 2. Does postbiotic ingestion alter the oral microbiome composition compared with placebo?

Participants needed: 56
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: The Archer-Daniels-Midland CompanyUpdated: Sep 21, 2026Locations: 1
Eligibility criteria

Adults who are between 18 - 65 years of age (inclusive) at the time of signing t... [+14]

Individuals who are intending to breastfeed, intending to conceive, or are pregn... [+19]

Status: Not yet recruiting

Effect of a Probiotic or Postbiotic on Gut Microbiome During Antibiotic Treatment

This study assesses the effects of a probiotic or postbiotic on gut microbiome during antibiotic treatment.

Participants needed: 126
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: The Archer-Daniels-Midland CompanyUpdated: May 19, 2026Locations: 1
Eligibility criteria

Males and females aged ≥18 to ≤ 65 years; if female, either not of childbearing... [+5]

Women who are pregnant, breastfeeding, or planning to become pregnant during the... [+13]

Status: Not yet recruiting

Changes in Amino Acid Absorption After Adding a Probiotic to an Acute Protein Feeding

The purpose of this study is to examine the rate and concentration of amino acid absorption after a three-week pattern of milk protein supplementation with and without the addition of a single strain probiotic.

Participants needed: 30
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: The Archer-Daniels-Midland CompanyUpdated: Nov 22, 2024Locations: 1
Eligibility criteria

Participants will be male or female between the ages of 18-35 years; [+5]

Participant is allergic to any ingredient in the nutritional supplement or place... [+3]

Status: Recruiting

Effect of a Multi-strain Probiotic on Recurrent Vulvovaginal Candidiasis

This study evaluates the effect of a multi-strain probiotic on the risk of recurrence and severity of symptoms in females with recurrent vulvovaginal candidiasis (R-VVC).

Participants needed: 126
Trial details
Age: 18-50Biological sex: FemaleType: InterventionalSponsor: The Archer-Daniels-Midland CompanyUpdated: Nov 7, 2024Locations: 6
Eligibility criteria

Premenopausal women aged 18-50 years. [+8]

Post-menopausal and peri-menopausal women. [+21]

Status: Not yet recruiting

Determination of the Safety and Efficacy of Two Probiotic Strains

The goal of this study is to determine the safety and efficacy of two probiotic strains in adults with mild to moderate gastrointestinal discomfort. The main questions it aims to answer is whether 6-week administration of a probiotic can improve how the participant feels regarding their gut health. This is done by completing a weekly questionnaire and the results are compared between the 6 weeks the participants are on a placebo and the 6 weeks the participants are on the probiotic. Participants will also provide a blood sample, and stool sample at the start and end of each treatment. Similarly, the results from the blood samples and stool samples will be analysed to determine if there is any improvement in markers related to gut health.

Participants needed: 100
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: The Archer-Daniels-Midland CompanyUpdated: Jun 20, 2024
Eligibility criteria

Signed Informed consent form [+2]

Presence of a serious congenital anomaly or chronic medical condition that would... [+9]