Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The Effect of Nalbuphine Extended-Release (NAL ER) on Cough in Participants With Refractory Chronic Cough (RCC)

The purpose of this study is to evaluate the efficacy and safety of Nalbuphine ER Extended-release tablets for the treatment of participants with RCC.

Participants needed: 100
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Trevi TherapeuticsUpdated: Aug 10, 2026Locations: 10
Eligibility criteria

Insufficient improvement in cough after treatment for any identified cough-assoc... [+5]

Clinical diagnosis of sleep apnea and/or use of continuous positive airway press... [+9]

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Status: Recruiting

Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine Extended-Release (NAL ER) Tablets

The primary purpose is to evaluate the safety and efficacy of NAL ER for the treatment of chronic cough in participants with Idiopathic Pulmonary Fibrosis (IPF).

Participants needed: 306
Trial details
Phase: Phase 3Age: 40+Biological sex: AllType: InterventionalSponsor: Trevi TherapeuticsUpdated: Jul 10, 2026Locations: 5
Eligibility criteria

Diagnosis of IPF as determined by the Investigator based on American Thoracic So... [+5]

Clinical diagnosis or clinical suspicion of an upper or lower respiratory tract... [+2]

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