Status: Not yet recruiting
A First-in-Human Study of a Novel 3rd Molar Tooth Bud Ablation Procedure
The goal of this single-arm prospective, non-randomized study is to demonstrate microwave ablation and agenesis of 3rd molar tooth buds using the Zero3 System in participants that have 3rd molar tooth bud(s) without the formation of enamel (calcification). The main question it aims to answer is the safety of the ablation procedure. Also effectiveness of 3rd molar tooth bud ablation and resulting agenesis will be assessed.
Participants needed: 35
Trial details
Age: 8-12Biological sex: AllType: InterventionalSponsor: TriAgenics IncUpdated: Sep 25, 2026Locations: 1
Eligibility criteria
Participant has radiographic evidence of at least one mandibular 3rd molar tooth... [+3]
Participant where use of local anesthetic is contraindicated, or [+7]