Clinical trials

16

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

The purpose of this study is to evaluate the ability of dapirolizumab pegol (DZP) as an add-on treatment to standard of care (SOC) medication to achieve clinically relevant long term improvement of moderate to severe disease activity.

Participants needed: 450
Trial details
Phase: Phase 3Age: 16+Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Aug 21, 2026Locations: 238
Eligibility criteria

Study participant must be ≥16 years of age, (≥18 years of age for China), unless... [+7]

Study participant has any medical or psychiatric condition (including conditions... [+11]

Status: Recruiting

A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Study Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis

The purpose of the study is to investigate the efficacy of galvokimig versus placebo in the time to the first acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in study participants with moderate-to-severe COPD with chronic bronchitis.

Participants needed: 402
Trial details
Phase: Phase 2Age: 40-80Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Aug 17, 2026Locations: 3
Eligibility criteria

Participant must be aged ≥40 to ≤80 years of age, inclusive, at the time of sign... [+9]

Participant has any history or presence of any medical or psychiatric condition,... [+11]

Status: Recruiting

A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis

The purpose of the study is to evaluate the dose-response relationship of galvokimig compared with placebo in study participants with moderate-to-severe atopic dermatitis (AtD).

Participants needed: 160
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Aug 14, 2026Locations: 68
Eligibility criteria

Participant must be aged greater than or equal (≥)18 years at the time of signin... [+5]

Participant has any history or presence of any medical or psychiatric condition,... [+8]

Status: Recruiting

A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

The purpose of the study is to assess the success of a single administration of Staccato alprazolam compared with placebo both in rapidly terminating a seizure episode within 90 seconds and with no recurrence of seizure(s) up to 2 hours after investigational medicinal product (IMP) administration.

Participants needed: 350
Trial details
Phase: Phase 3Age: 12+Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Aug 14, 2026Locations: 183
Eligibility criteria

Participant must be ≥12 years of age at the Baseline/Randomization Visit [+10]

Participant has a current history of alcohol or drug use disorder, as defined in... [+24]

Status: Recruiting

A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Adult Study Participants With Non-Cystic Fibrosis Bronchiectasis

The purpose of the study is to investigate the efficacy of galvokimig versus placebo on the time to the first pulmonary exacerbation in study participants with non-cystic fibrosis bronchiectasis (NCFB)

Participants needed: 300
Trial details
Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Aug 11, 2026Locations: 3
Eligibility criteria

Participant must be 18 to ≤80 years of age, inclusive, at the time of signing th... [+1]

Participant with a history of chronic expectoration who are current sputum produ... [+21]

Status: Recruiting

SLC6A1-NDD Prospective Longitudinal Natural History Study

The overall objective of this prospective longitudinal natural history study is to collect clinical data to characterize and evaluate the natural course of SLC6A1-NDD and assess the feasibility of certain assessments for the purpose of conducting future clinical studies in patients with this disease.

Participants needed: 60
Trial details
Age: Up to 17Biological sex: AllType: ObservationalSponsor: UCB Biopharma SRLUpdated: Jul 31, 2026Locations: 3
Eligibility criteria

Patient with a diagnosis of SLC6A1-NDD characterized by epilepsy, global develop... [+3]

Patients and their caregivers are unable to complete follow-up visits. [+2]

Status: Recruiting

A Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis

The purpose of this study is to assess the pharmacokinetics, pharmacodynamics, safety, tolerability, immunogenicity and activity of zilucoplan (ZLP) in pediatric study participants with generalized myasthenia gravis (gMG).

Participants needed: 8
Trial details
Phase: Phase 2, Phase 3Age: 12-17Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Jul 31, 2026Locations: 9
Eligibility criteria

Participant has a diagnosis of generalized myasthenia gravis (gMG) confirmed by... [+4]

Participant has known positive serology for muscle-specific kinase [+4]

Status: Recruiting

A Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With Seizures

The purpose of the study is to evaluate the long-term safety and tolerability of brivaracetam.

Participants needed: 70
Trial details
Phase: Phase 3Age: 1+Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Jul 27, 2026Locations: 36
Eligibility criteria

Study participants ≥ 1 month of age with a confirmed diagnosis of epilepsy who p... [+4]

Severe medical, neurological, or psychiatric disorders or laboratory values, whi... [+7]

Status: Recruiting

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis

The purpose of this study is to evaluate the efficacy and safety of bimekizumab compared with placebo in participants with palmoplantar pustulosis (PPP).

Participants needed: 320
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Jul 17, 2026Locations: 87
Eligibility criteria

At least 18 years of age inclusive, at the time of signing the informed consent... [+5]

Has PPP symptoms which improve significantly between the Screening Visit and Bas... [+5]

Status: Recruiting

A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

Primary purpose of the study is to assess the concentration of bimekizumab in mature human breast milk.

Participants needed: 20
Trial details
Phase: Phase 1Age: 18+Biological sex: FemaleType: InterventionalSponsor: UCB Biopharma SRLUpdated: Jul 17, 2026Locations: 14
Eligibility criteria

Study participant must be at least 18 years of age at the time of signing the in... [+5]

Study participant has any medical, obstetrical, or psychiatric condition that, i... [+6]

Trial details
Phase: Phase 3Age: 2-18Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Jul 17, 2026Locations: 23
Eligibility criteria

Study participant must be 2 to <18 years of age inclusive, at the Baseline Visit... [+10]

Study participants fulfilling any International League of Associations for Rheum... [+11]

Status: Recruiting

A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

To demonstrate that bimekizumab administered intravenously is noninferior to subcutaneous administration.

Participants needed: 392
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Jul 6, 2026Locations: 63
Eligibility criteria

Be 18+ years old and legally able to consent [+3]

Serious organ system disorders (e.g., heart, liver, kidney, gastrointestinal, ne... [+5]

Status: Recruiting

A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis

The purpose of the study is to demonstrate the efficacy, safety and tolerability of rozanolixizumab compared with placebo in the treatment of adult study participants with Ocular Myasthenia Gravis.

Participants needed: 120
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Jun 16, 2026Locations: 2
Eligibility criteria

Participant must be a minimum of 18 years of age inclusive at the time of signin... [+11]

Participant has any clinically significant medical or psychiatric condition (inc... [+7]

Status: Recruiting

Phase 4 Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Chinese Participants With Generalized Myasthenia Gravis

The purpose of the study is to assess the clinical efficacy of rozanolixizumab in adult Chinese participants with generalized myasthenia gravis (gMG) in the first Treatment Cycle.

Participants needed: 40
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: May 22, 2026Locations: 12
Eligibility criteria

Study participant must be ≥18 years of age at the time of signing the informed c... [+6]

Study participant has a known hypersensitivity to any components of the study dr... [+6]

Status: Recruiting

A Study to Assess Zilucoplan Concentration in Breast Milk of Healthy Lactating Women

The purpose of this study is to assess the steady state (SS) concentrations of zilucoplan (ZLP) and its major metabolites in mature breast milk of healthy study participants following injection of repeated once-daily doses of ZLP.

Participants needed: 15
Trial details
Phase: Phase 1Age: 18+Biological sex: FemaleType: InterventionalSponsor: UCB Biopharma SRLUpdated: Mar 24, 2026Locations: 2
Eligibility criteria

Study participant must be minimum 18 years at the time of signing the Informed c... [+6]

Study participant has a history or presence of/significant history of or current... [+12]

Status: Not yet recruiting

A Study to Evaluate The Long-Term Safety And Efficacy of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis

The purpose of the study is to assess the long-term safety and efficacy of rozanolixizumab in adult study participants with ocular myasthenia gravis.

Participants needed: 100
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: UCB Biopharma SRLUpdated: Mar 11, 2026
Eligibility criteria

Participant must be a minimum of 18 years of age inclusive at the time of signin... [+8]

Participant meets any of the withdrawal criteria defined in MG0038 [+4]