Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Available

Expanded Access Protocol (EAP) for Nonconforming (NC) Afami-cel

The purpose of this expanded access protocol (EAP) is to provide controlled access to Afamitresgene autoleucel, suspension for intravenous infusion that does not meet the commercial release specification (NC afami-cel). This EAP will be conducted at authorized treatment centers where TECELRA® is being administered and where the EAP is approved to be conducted. Patients who are prescribed TECELRA® , sign the informed consent form, and meet all entry criteria will be eligible to participate in this protocol.

Trial details
Age: 18+Biological sex: AllType: Expanded AccessSponsor: USWM CT, LLCUpdated: Aug 11, 2026Locations: 11
Eligibility criteria

Patient must provide written informed consent prior to participating in this pro... [+7]

Patient has contraindication(s) as per the TECELRA® USPI [+1]

Read more
Status: Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers.

Participants needed: 20
Trial details
Phase: Phase 1, Phase 2Age: 2-21Biological sex: AllType: InterventionalSponsor: USWM CT, LLCUpdated: Aug 11, 2026Locations: 10
Eligibility criteria

Subject has histologically confirmed diagnosis of any one of the following cance... [+5]

Positive for HLA-A*02:05 in either allele; or any A*02 having same protein seque... [+8]

Read more