Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

This study is a randomized, double-blind, placebo-controlled study designed to assess the efficacy and safety of ensifentrine inhalation suspension (3 mg) delivered twice daily via standard jet nebulizer up to 52 weeks, compared to placebo, in participants with non-cystic fibrosis bronchiectasis (NCFBE).

Participants needed: 284
Trial details
Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USAUpdated: Aug 6, 2026Locations: 51
Eligibility criteria

Males are eligible to participate if they agree to use contraception as describe... [+7]

A diagnosis of COPD or a primary diagnosis of asthma, as judged by the investiga... [+27]

Status: Recruiting

Effect of Ensifentrine on Sputum Markers of Inflammation in COPD

This is a randomized, double-blind, placebo-controlled, two-period cross-over study of nebulized ensifentrine (3 mg) or placebo administered BID for two 8-week Treatment Periods. All participants with receive both ensifentrine and placebo during participation. There are 7 in-clinic visits over a total duration of up to 24 weeks participation.

Participants needed: 56
Trial details
Phase: Phase 2Age: 40-80Biological sex: AllType: InterventionalSponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USAUpdated: May 13, 2026Locations: 3
Eligibility criteria

Not listed