Health TrialsbyHealthPanel

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of Sovilnesib in Subjects With Ovarian Cancer

This is a phase 1b study to assess the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of sovilnesib at different dose levels to establish the optimal dose of sovilnesib in subjects with selected advanced solid tumors.

Participants needed: 150
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Volastra Therapeutics, Inc.Updated: Oct 13, 2026Locations: 11
Eligibility criteria

All Parts: Age ≥ 18 years, ECOG Performance Status ≤ 1, at least 1 site of measu... [+2]

Part 1 only: MSI-H, dMMR, POLE gene hotspot mutated, or known hypermutator pheno... [+5]

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Status: Recruiting

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers.

Participants needed: 200
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Volastra Therapeutics, Inc.Updated: Nov 4, 2025Locations: 14
Eligibility criteria

All Parts: Age ≥ 18 years, ECOG Performance Status ≤ 1, at least 1 site of measu... [+2]

MSI-H, dMMR, POLE gene hotspot mutated, or known hypermutator phenotype [+6]

Read more