Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

XTX501 in Patients With Metastatic Non-Small Cell Lung Cancer and Advanced Solid Tumors

This is a first-in-human, multicenter, Phase 1/2, open-label study designed to evaluate the safety and tolerability of XTX501 as monotherapy in participants with metastatic non-small cell lung cancer (NSCLC) and select advanced solid tumors.

Participants needed: 140
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Xilio Development, Inc.Updated: Jul 7, 2026
Eligibility criteria

Measurable disease at baseline per RECIST v1.1 [+6]

Prior treatment with IL-2 [+4]

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Status: Recruiting

XTX301 in Patients With Advanced Solid Tumors

This is a first-in-human, multicenter, Phase 1/2, open-label study designed to evaluate the safety and tolerability of XTX301 as monotherapy in patients with advanced solid tumors.

Participants needed: 358
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Xilio Development, Inc.Updated: Jun 23, 2026Locations: 12
Eligibility criteria

ECOG performance status of 0-2 for Phase 1 [+4]

Prior treatment with IL-12 therapy (any form, e.g. recombinant human, prodrug, i... [+9]

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