Clinical trials

8

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

The purpose of this study is to evaluate the efficacy and safety of ZL-1310 compared to Investigator's Choice Therapy in participants with relapsed Small Cell Lung Cancer.

Participants needed: 480
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Sep 14, 2026Locations: 155
Eligibility criteria

Age >/= 18 years, or considered an adult by local regulations, at the time of co... [+9]

Received more than one line of systemic therapy for Extensive-Stage SCLC. [+9]

Status: Not yet recruiting

A Prospective, Observational, Single-Arm, Multicenter Real-World Study Evaluating the Treatment Pattern, Safety and Effectiveness of Xanomeline and Trospium Chloride Capsules (KarXT) in the Treatment of Chinese Adult Participants With Schizophrenia

This study is a prospective, observational, single-arm, open-label, multicenter, real-world study conducted in Chinese adult participants with schizophrenia who meet the International Classification of Diseases (ICD)-10 diagnostic criteria. The total study duration is up to 17 weeks, including a screening/baseline data collection period followed by an observational part during which KarXT treatmentpattern, schizophrenia treatment decisions and compliance will be observed in the real-world setting.

Participants needed: 250
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Sep 3, 2026Duration: 17 Weeks
Eligibility criteria

Adult participants (age: ≥18 and ≤65 years) who meet the ICD-10 diagnostic crite... [+1]

Participants who have contraindications listed in the prescribing information: u... [+5]

Status: Not yet recruiting

A Study of ZL-1310 in Combination With a Checkpoint Inhibitor Versus Standard of Care Platinum Based Chemotherapy With a Checkpoint Inhibitor as First-line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer

The purpose of this study is to evaluate the efficacy and safety of ZL-1310 in combination with a checkpoint inhibitor compared to standard first-line therapy in participants with Extensive-Stage Small Cell Lung Cancer.

Participants needed: 530
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Aug 31, 2026
Eligibility criteria

Histologically or cytologically confirmed ES-SCLC [+5]

Has a contraindication to receive atezolizumab or durvalumab according to local... [+6]

Status: Recruiting

A Study of ZL-1310 in Participants With Selected Solid Tumors

A Phase 1b/2, Open-label, Multi-center Study of ZL-1310 in Participants With Selected Solid Tumors

Participants needed: 166
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Aug 21, 2026Locations: 23
Eligibility criteria

Signed informed consent [+6]

Participants with another known malignancy that is progressing or requires activ... [+13]

Status: Recruiting

A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

An open-label, multicenter study of ZL-1310 as a single agent and in combination with Atezolizumab (with and without Carboplatin) to evaluate the safety, efficacy, and pharmacokinetics in subjects with small cell lung cancer

Participants needed: 339
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Aug 21, 2026Locations: 38
Eligibility criteria

Signed informed consent [+6]

Participants with another known malignancy that is progressing or requires activ... [+16]

Status: Not yet recruiting

A Phase 1 Study to Evaluate Pharmacokinetics, Safety and Tolerability of ZL-1503 in Healthy Volunteers

This is a phase 1, single dose, randomized, open-label, parallel-group study to evaluate the pharmacokinetics (PK), safety, tolerability and immunogenicity of ZL-1503 and to explore its PD biomarkers following a single subcutaneous (SC) or intravenous (IV) administration in healthy volunteers.

Participants needed: 36
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Aug 20, 2026Locations: 1
Eligibility criteria

Healthy male and female volunteers, 18-65 years of age [+2]

Significant health issues, such as positive tests for human immunodeficiency vir... [+6]

Status: Recruiting

A Phase 1/1b Study to Evaluate Safety, Tolerability and Pharmacokinetics of ZL-1503 in Healthy Volunteers and Participants With Moderate to Severe Atopic Dermatitis

This is a phase 1/1b randomized, double blind, placebo-controlled, single dose escalation (SAD) and multiple dose escalation (MAD) study to evaluate the safety, tolerability, and pharmacokinetics (PK) of ZL-1503 in healthy volunteers and participants with moderate to severe atopic dermatitis (AD)

Participants needed: 84
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Aug 7, 2026Locations: 12
Eligibility criteria

Healthy male and female volunteers, 18-65 years of age [+11]

Significant health issues, such as positive tests for human immunodeficiency vir... [+9]

Status: Recruiting

Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors

The purpose of this study is to evaluate the safety and tolerability of investigational study drug ZL-6201 for treating sarcoma and solid tumors cancer.

Participants needed: 180
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Jul 23, 2026Locations: 8
Eligibility criteria

Adult men and women ≥18 years of age at the time of signing the ICF with an East... [+7]

Participants with another known malignancy that has required treatment within th... [+7]