Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Polygonatum Sibiricum Reduces Visceral Fat in Obese Adults

This study is being done to find out if a traditional Chinese herb called Polygonatum sibiricum (Huangjing) can help reduce belly fat and improve metabolic health in adults with visceral obesity. Visceral obesity means having too much fat stored deep inside the belly, around the organs. This type of fat is linked to a higher risk of diabetes, fatty liver, and heart disease. The study will include 66 adults with visceral obesity. Participants will be randomly assigned to one of two groups: One group will receive a Polygonatum sibiricum decoction (15 grams daily) plus standard lifestyle advice on diet and exercise. The other group will receive the same lifestyle advice only. The study will last for 12 weeks. Researchers will measure changes in visceral fat area, body weight, waist size, blood sugar, blood lipids, and liver fat. They will also look at gut bacteria and related markers to better understand how Polygonatum sibiricum might work. Participation involves 4 visits to the study site over the 12-week period. All participants will receive free health assessments and dietitian guidance. The study is not a treatment but a research study to test whether this herb has potential benefits for visceral obesity.

Participants needed: 66
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Zhejiang Provincial Tongde HospitalUpdated: Aug 12, 2026Locations: 1
Eligibility criteria

Age 18 to 65 years, male or female; [+3]

Secondary obesity (e.g., caused by endocrine disorders such as hypothyroidism, C... [+9]

Status: Not yet recruiting

Silkworm Pupa Powder Improves Alzheimer's Disease

The goal of this clinical trial is to learn if silkworm pupa powder works to treat Alzheimer's disease in patients. It will also learn about the safety of silkworm pupa powder, and its effect on patients' nutritional and frailty status. The main questions it aims to answer are: * Does silkworm pupa powder improve cognitive function and daily living abilities? * Does silkworm pupa powder improve nutritional status and frailty? * What medical problems do participants have when taking silkworm pupa powder? Researchers will evaluate the treatment by comparing the participants' conditions after taking the powder to their baseline conditions (a single-arm study without a placebo) to see if silkworm pupa powder works to treat Alzheimer's disease. Participants will: * Take silkworm pupa powder every day for 12 weeks * Visit the clinic once every 4 weeks for checkups and tests * Use an electronic punch-card system daily and report any symptoms

Participants needed: 100
Trial details
Age: 50-90Biological sex: AllType: InterventionalSponsor: Zhejiang Provincial Tongde HospitalUpdated: Jun 10, 2026Locations: 1
Eligibility criteria

Diagnosis of probable Alzheimer's disease (AD) according to the National Institu... [+9]

Diagnosis of dementia other than Alzheimer's disease (AD) or other central nervo... [+16]

Status: Recruiting

Silkworm Pupa Powder Improves Dementia.

The purpose of this clinical trial is to determine whether silkworm pupa powder is effective in treating Alzheimer's disease. It will also investigate whether silkworm pupa powder can improve the nutritional and frailty status of patients with Dementia. The main questions it aims to answer are: * Will silkworm pupa powder improve the daily living conditions of patients with Alzheimer's disease? * Will silkworm pupa powder improve the nutritional status and frailty of Alzheimer's disease patients? Researchers will compare silkworm pupa powder with a placebo (a similar substance containing 0.5% silkworm pupa powder) to see if silkworm pupa powder can treat Alzheimer's disease. Participants will: * Take silkworm pupa powder or placebo daily for four months; * Visit the clinic for check-ups and tests every four weeks; * Record their symptoms and various physiological indicators.

Participants needed: 300
Trial details
Age: 50-90Biological sex: AllType: InterventionalSponsor: Zhejiang Provincial Tongde HospitalUpdated: Jun 8, 2026Locations: 1
Eligibility criteria

Diagnosis of probable Alzheimer's disease (AD) according to the National Institu... [+9]

Diagnosis of dementia other than Alzheimer's disease (AD) or other central nervo... [+17]