970-nm Diode Laser Versus Liquid Nitrogen Cryotherapy in Maxillary Labial Frenectomy
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorKutahya Health Sciences University
About this trial
This prospective, randomized, single-blind, assessor-blinded, parallel-group clinical trial aims to compare the effects of 970-nm diode laser and liquid nitrogen cryotherapy in patients requiring maxillary labial frenectomy.
The primary objective is to compare the change in salivary cortisol levels from baseline to postoperative day 2 between the two treatment groups. Secondary objectives include comparison of postoperative pain, edema, interincisal mouth opening, analgesic consumption, operation duration, state anxiety, clinical wound healing, and adverse events.
Eligible adult patients with an indication for maxillary labial frenectomy will be randomly assigned to receive either 970-nm diode laser frenectomy or liquid nitrogen cryotherapy. Salivary cortisol samples and clinical outcomes will be assessed during the early postoperative follow-up period.
Eligibility criteria
Qualifiers
Age between 18 and 65 years.
Systemically healthy, ASA I status.
Clinical indication for maxillary labial frenectomy.
Ability to attend postoperative follow-up visits.
Disqualifiers
Systemic or local corticosteroid use within the last 6 months.
Endocrine disease that may affect cortisol levels.
Pregnancy or lactation.
Active oral infection.
Trial design
Treatments tested in this trial
- 970-nm Diode Laser Frenectomy
- Liquid Nitrogen Cryotherapy
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov